TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: <180nMAssay Description:Cell Culture and TransfectionAll cell lines used in this study was purchased from American Type Culture Collection (ATCC). Mycoplasma contamination w...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 190nMAssay Description:Cell Culture and TransfectionAll cell lines used in this study was purchased from American Type Culture Collection (ATCC). Mycoplasma contamination w...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 300nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 340nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 400nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 420nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 440nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 450nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 450nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 470nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 480nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 510nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 530nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 550nMAssay Description:Inhibition of full length recombinant human LOX expressed in HEK cells assessed as reduction in H2O2 production using DAP as substrate preincubated f...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 550nMAssay Description:Inhibition of human LOX expressed in HEK cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs foll...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 550nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 590nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 620nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 690nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 700nMAssay Description:Cell Culture and TransfectionAll cell lines used in this study was purchased from American Type Culture Collection (ATCC). Mycoplasma contamination w...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 720nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 740nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 760nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 770nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 770nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 820nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 830nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 890nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 910nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 910nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 930nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.00E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.00E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.00E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.00E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.00E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.10E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.10E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.10E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.10E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.10E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.20E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of LOX in human IMR90 cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.30E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.40E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.40E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.40E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 1.40E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair